“Talkies” is a live comedy event like no other. Held monthly, the show goes against the grain in terms of expectations one might have of a humor-focused show. It foregrounds creativity and multimedia use, resulting in a unique presentation of “funny” content. Nick Stargu and fellow “Talkies” hosts Aviva Siegel, George Chen and Land Smith are bringing their next installation of the show to Cobb’s Comedy Club, located in San Francisco’s North Beach neighborhood, on Thursday. The upcoming “Talkies” features special guests Chad Opitz, Darlene Bereznicki and Jack Brown as well as short films by Kate Rhoades and the Dress Up Gang.